ETHNOMEDICINE STUDY AND ANTIOXIDANT ASSAY OF KATUK LEAVES FROM CIREUNDEU TRADITIONAL VILLAGE Hillda Herawati, Euis Reni Yuslianti, Randi Muchtar Surya Wiguna
Universitas Jenderal Achmad Yani
Abstract
Katuk leaves (Sauropus androgynous) are traditionally used in Cirendeu Village for purported health benefits, including enhancing breastfeeding and treating oral throat inflammation. Katuk leaves high antioxidant potential may offer therapeutic benefits in orthodontic treatment. This study aims to investigate traditional used of katuk leaves in Cirendeu and evaluate their antioxidant activity. The study were a observational research for etnomedicine study and experiment study for antioxidant assay. Ethnomedicine phytochemical screening, DPPH, and FRAP Statistical analysis with independent t test. Ethnomedicine findings revealed that 90,28% of respondents use katuk leaves as a traditional remedy, particularly for enhancing location and treating oral throat disease. Katuk leaves phytochemical screening contain flavonoids, alkaloids, tannins, polyphenols, quinones, monoterpenoids, sesquiterpenoids, sterodis, and triterpenoids. DPPH assay results indicated an IC50 value of 3,78(0,01) myugram/ml, demonstrating strong antioxidant activity. FRAP assay showed an 47,85 mgOE/g extract antioxidant capacity. There are significant difference between quercetein control and katuk leaves extract group. The study confirms katuk leaves high antioxidant activity, aligning with their traditional use in enhancing health and treating inflammatory conditions. These findings support potential of katuk leaves as an anti-inflammatory agent, warranting further research to explore their application in modern medical treatments including an antiinflammatory agent for orthodontic treatment.
