The Potency of Kuldon solution in the healing process of aphthous stomatitis Please Just Try to Submit This Sample Abstract
Dewi Priandini,1,* Rahmi Amtha,1 , Aprilia Puspita Sulistia,2 Abrijanto, 3
Abstract
Background: Aphthous stomatitis is one of the most prevalent oral mucosal diseases. The Kuldon solution, currently available on the market, is presumed to alleviate aphthous ulcers.
Objectives: This study aims to evaluate the efficacy of Kuldon solution in the healing process of aphthous stomatitis. Methods: A double-blind, randomized controlled trial (RCT) was conducted with 60 subjects (27 males and 33 females), who were randomly assigned to receive either Drug A (Kuldon solution) or Drug B (HA rinse) under consent. Pain levels were assessed using a Visual Analogue Scale (VAS), and the diameter of the lesions was measured on days 2, 5, and 7. Statistical analysis was performed using the Mann-Whitney test with a significance level p < 0.05. Results: On the second day, 73.3% of the subjects using Drug A reported no pain, compared to 60% of those using Drug B. By the fifth day, all subjects (100%) using Drug A experienced no pain, while 90% of those using Drug B reported the same. Lesion diameter reduction was 40% for both treatments by day 2. By day 5, 90% of subjects using Drug A showed a reduction in lesion diameter, compared to 16.6% of those using Drug B. The statistical analysis indicated a significant difference between the groups, with a p-value of 0.000. Conclusions: Kuldon solution demonstrates significant potency in the healing of aphthous stomatitis lesions
