Microglandular Hyperplasia of the Cervix: A Case Report and Literature Review Muhammad Syah Misuari Sabirin (a*,b), Meike Rachmawati (a,b), Ismet Muchtar Nur (a), Abdul Hadi Hassan (a), Yuktiana Kharisma (a), Meta Maulida (a), Ermina Widyastuti (a), Afiati (b)
a) Faculty of Medicine, Universitas Islam Bandung.
Jalan Tamansari No. 20, Bandung 40116, Indonesia
*sabslab.ms[at]gmail.com
b) Laboratorium Biopath.
Jalan Jend. Sudriman No. 655 A, Bandung 40164, Indonesia
Abstract
Microglandular hyperplasia (MGH) is a rare, benign non-neoplastic glandular proliferation of the endocervix that often found incidentally in reproductive women. MGH usually can be found in a patient with abnormal uterine bleeding or hormonal imbalance. This case report describes a 21-year-old woman who presented with solitary, polypoid mass from uterine cervix. Histopathological examination of a cervical biopsy revealed features characterized by the presence of numerous small, crowded, complex proliferation of glands with minimal cytological atypia and increased glandular to stromal ratio. These features are consistent with MGH. The patient had no significant medical history, and her clinical presentation suggested no underlying hormonal imbalance. A single excision is performed with no followed conservative therapy. This case highlights the importance of considering MGH in young women presenting with polypoid lesion from cervix and emphasizes the role of histopathological examination in distinguishing this condition from malignant variants. The management approach in this patient provided a satisfactory clinical outcome.
Keywords: Case report, cervix, histopathology, microglandular hyperplasia
