Antibacterial Effects of Glass Ionomer Cements Modified with Chitosan : A Systematic Review
1Florencia Livia Kurniawan**, 2Ferry Sandra, 3Mohammad Ischak, 1Octarina Octarina, 4Komariah, 1Rosalina Tjandrawinata

1Department of Dental Material Science and Technology, Faculty of Dentistry, Universitas Trisakti, Jakarta 11440, Indonesia
2Department of Oral Biology sub&#8208-division of Biochemistry and Molecular Biology, Faculty of Dentistry, Universitas Trisakti, Jakarta 11440, Indonesia
3Department of Architecture, Faculty of Engineering and Planning, Universitas Trisakti, Jakarta 11440, Indonesia
4Department of Oral Biology sub&#8208-division of Histology, Faculty of Dentistry, Universitas Trisakti, Jakarta 11440, Indonesia

Abstract

Objective: Glass ionomer cements (GICs) have long been used in dentistry for their advantageous properties, including adhesion to tooth structure and fluoride release. However, their susceptibility to bacterial colonization poses a challenge in dental restorative materials. Chitosan is a biopolymer known for its antimicrobial properties. The study aims to investigate the potential of GICs modified with chitosan (GIC-CH) as an effective dental material with enhanced antibacterial activity against common oral pathogens. This systematic review explores the antibacterial effects of GIC-CH. By synthesizing and analyzing existing literature, this review aims to provide a comprehensive understanding of the efficacy of chitosan-modified GICs against oral pathogens. Various studies investigating the antibacterial activities are critically evaluated. The findings suggest that chitosan incorporation enhances the antibacterial properties of GICs.
Method: The method used is to collect literature from search engines such as Pubmed, Scielo, Google Scholar, Science Direct, Elsevier which discusses the antibacterial effect of chitosan-modified GICs, then reviewed. From the results of the journal search, 7 literatures relevant to the topic were obtained.
Result: The results reveal that chitosan-modified GICs exhibit significant antibacterial activity, with effectiveness increasing proportionally by chitosan concentration. Mechanical properties and fluoride release remained satisfactory, indicating potential clinical viability.
Conclusion: This study underscores the promise of chitosan-modified GICs in enhancing the antibacterial properties of dental restorative materials.

Keywords: glass ionomer cement, chitosan, antibacterial activity, dental restorative material, oral pathogens

Topic: Advance Materials for Health Applications