SCOPING REVIEW : ^ The Efficacy of Enzyme CoQ10 as Adjunctive Therapy for Periodontitis in Individual with Diabetes Mellitus ^
Fergy Christin Maitimu, Trijani Suwandi

Department of Periodontics, Faculty of Dentistry, Universitas Trisakti, Jakarta, Indonesia

Abstract

ABSTRACT
Background : Periodontitis has clinical feature of the loss of periodontal tissue support that can lead to alveolar bone loss until tooth loss. Individual with Diabetes Mellitus has higher risk to have periodontitis and periodontitis could affect the glycaemic control of the individual with Diabetes Mellitus. Coenzyme Q 10 or enzyme CoQ10 is an antioxidant that could supresses periodontal inflammation. Objective : To obtain some scientific data related to the efficacy of Enzyme CoQ10 as Adjunctive Therapy for Periodontitis Treatment in Individual with Diabetes Mellitus. Methods : Using PRISMA (The Preferred Reporting Items for Systematical Reviews and Meta-Analysis) to obtain the efficacy of enzyme CoQ10 as adjunctive therapy for periodontitis in individual with Diabetes Mellitus. Two databases (Pubmed and Google Scholar) were used from January 2014 until May 2024. Result : Initially, all the studies with the title according to the search were found and all the Randomized-Clinical Trial (RCT) and Non-Randomized Clinical Trial studies were filtered to find the efficacy of enzyme CoQ10 as adjunctive therapy for periodontitis in individual with diabetes mellitus. Conclusion : Enzyme CoQ10 can be used as adjunctive therapy for periodontitis in individual with Diabetes Mellitus and has possibility to be a sole adjunctive therapy agent for periodontitis in individual with Diabetes Mellitus.

Keywords: CoQ10, Periodontitis, Diabetes Mellitus, Adjunctive Therapy

Topic: Periodontics