Potential of the Combination of Nanohydroxyapatite and Salacca zalacca Skin Extract to Reduce Dentin Hypersensitivity
Elline Elline1, Anastasia Elsa Prahasti1,Eko Fibryanto1,Maria Gresela Mulia2,Syuwari Azhar Azman3

1Department of Conservative Dentistry, Faculty of Dentistry, Universitas Trisakti, Indonesia
2Student of Bachelor Degree of Dentistry, Faculty of Dentistry, Universitas Trisakti, Indonesia
3Conservative Dentistry Unit, Restorative Dentistry Department, Kulliyyah of Dentistry, IIUM Kuantan, Malaysia

Abstract

Introduction: Exposed dentinal tubules, which occur due to the loss of protective layers such as enamel and cementum, frequently cause dentin hypersensitivity. Studies are required for optimal results even though hydroxyapatite can cover exposed dentinal tubules. Extracts from the skin of Salacca zalacca, which are rich in antioxidants, show promise as an adjunct to enhance the effectiveness of hydroxyapatite and potentially promote bone regeneration. This study aims to determine the potential of the combination of hydroxyapatite and Salacca zalacca skin extract (HAp-SAL) for reducing dentin hypersensitivity by covering the dentinal tubules. Materials and Methods: This research was an in vitro experimental investigation. HAp-SAL was mixed in different ratios. Group A is a control, while Group B, C, and D are groupings of HAp and SAL in 2:1, 1:1, and 1:2 ratio. They were administered to dentin samples for 14 days. Scanning electron microscopy-energy dispersive X-ray (SEM-EDX) analysis was performed. The data was categorized into three categories of dentinal tubule closure. The content of minerals in dentinal tubules was also examined. The data were analyzed using the Kruskal-Wallis test to determine the differences between groups using the IBM SPSS Statistics Version 27 software. Results: The statistics revealed that there were significant differences (p < 0.05) between groups A, B, C, and D. It was demonstrated by the formation of mineral deposits on the tubule walls and the accumulation of calcium and phosphate ions surrounding the dentinal tubules that caused mineral deposits. Conclusion: The hydroxyapatite and Salacca zalacca skin extract (HAp-SAL) with 2:1, 1:1, and 1:2 ratio may be able to lessen dentin hypersensitivity by coating dentinal tubules.

Keywords: dentin- extract- hypersensitivity- hydroxyapatite- Salaca zalacca

Topic: Conservative Dentistry